Modeling Dose and Local Control in Radiotherapy
放射治疗中剂量与局部肿瘤控制的建模
We discuss models for predicting local control (prevention of tumor recurrence) after therapeutic radiation in cancer patients. The probability of control is first formulated from theoretical precepts. Biophysical principles dictate that the three factors in therapy that most universally influence outcome are total dose, number of sessions in which the dose is administered, and total time under treatment. We show that these principles also suggest the scale, or link…