The Errors-in-Variables Problem: Considerations Provided by Radiation Dose-Response Analyses of the A-Bomb Survivor Data
测量误差问题:原子弹幸存者辐射剂量反应分析的启示
Some basic issues in the errors-in-variables problem are discussed, in terms of considerations that arose in analyses of radiation effects on atomic bomb survivors. The setting essentially involves generalized linear models for the response variables, a very nonnormal distribution of the true covariable, and multiplicative errors in the observed covariable. Consideration is given to distinctions between structural and functional modeling. It is argued that careful attention…