Incorporating Historical Controls in Testing for a Trend in Proportions
比例趋势检验中历史对照信息的纳入
The testing of chemicals for carcinogenic activity in lifetime rodent bioassays has produced a large amount of data on a few strains of mice and rats. Because of the use of fixed protocols in repeated experiments, the opportunity presents itself for using this historical data in the analysis of a current experiment. What has been considered is the statistical incorporation of the historical control data into the current control group to increase the power of the test. This…