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False Discovery Rate Control via Data Splitting

通过数据拆分控制错误发现率

Selecting relevant features associated with a given response variable is an important problem in many scientific fields. Quantifying quality and uncertainty of a selection result via false discovery rate (FDR) control has been of recent interest. This article introduces a data-splitting method (referred to as “DS”) to asymptotically control the FDR while maintaining a high power. For each feature, DS constructs a test statistic by estimating two independent regression…

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A Scale-Free Approach for False Discovery Rate Control in Generalized Linear Models

广义线性模型中控制错误发现率的无尺度方法

The Generalized Linear Model (GLM) has been widely used in practice to model counts or other types of non-Gaussian data. This article introduces a framework for feature selection in the GLM that can achieve robust False Discovery Rate (FDR) control. The main idea is to construct a mirror statistic based on data perturbation to measure the importance of each feature. FDR control is achieved by taking advantage of the mirror statistic’s property that its sampling distribution…

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Monte Carlo Approximation of Bayes Factors via Mixing With Surrogate Distributions

通过与替代分布混合进行贝叶斯因子的蒙特卡洛近似

By mixing the target posterior distribution with a surrogate distribution, of which the normalizing constant is tractable, we propose a method for estimating the marginal likelihood using the Wang–Landau algorithm. We show that a faster convergence of the proposed method can be achieved via the momentum acceleration. Two implementation strategies are detailed: (i) facilitating global jumps between the posterior and surrogate distributions via the multiple-try Metropolis…

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