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指数生存曲线的序贯比较AI 解读

A general approach is outlined to the problem of sequentially comparing exponential “survival” curves in a clinical trials setting. It entails applying sequential tests of hypotheses concerning the drift of a Wiener process to a particular discrete-time process generated from the survival data. Anderson's [1] modified sequential probability ratio test [SPRT) is used for illustration. Monte Carlo studies indicate that the method is valid for samples of moderate size and that…

指数生存曲线的序贯比较AI 解读

A general approach is outlined to the problem of sequentially comparing exponential “survival” curves in a clinical trials setting. It entails applying sequential tests of hypotheses concerning the drift of a Wiener process to a particular discrete-time process generated from the survival data. Anderson's [1] modified sequential probability ratio test [SPRT) is used for illustration. Monte Carlo studies indicate that the method is valid for samples of moderate size and that…