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Decoupling Shrinkage and Selection in Bayesian Linear Models: A Posterior Summary Perspective

贝叶斯线性模型中收缩与选择的解耦:后验摘要视角

Selecting a subset of variables for linear models remains an active area of research. This article reviews many of the recent contributions to the Bayesian model selection and shrinkage prior literature. A posterior variable selection summary is proposed, which distills a full posterior distribution over regression coefficients into a sequence of sparse linear predictors.

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Partial Factor Modeling: Predictor-Dependent Shrinkage for Linear Regression

部分因子建模:线性回归中依赖预测变量的收缩

We develop a modified Gaussian factor model for the purpose of inducing predictor-dependent shrinkage for linear regression. The new model predicts well across a wide range of covariance structures, on real and simulated data. Furthermore, the new model facilitates variable selection in the case of correlated predictor variables, which often stymies other methods.

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High-Dimensional Sparse Factor Modeling: Applications in Gene Expression Genomics

高维稀疏因子建模:基因表达组学应用

We describe studies in molecular profiling and biological pathway analysis that use sparse latent factor and regression models for microarray gene expression data. We discuss breast cancer applications and key aspects of the modeling and computational methodology. Our case studies aim to investigate and characterize heterogeneity of structure related to specific oncogenic pathways, as well as links between aggregate patterns in gene expression profiles and clinical…

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Flexible covariance estimation in graphical Gaussian models

高斯图模型中的灵活协方差估计

In this paper, we propose a class of Bayes estimators for the covariance matrix of graphical Gaussian models Markov with respect to a decomposable graph G. Working with the WPG family defined by Letac and Massam [Ann. Statist. 35 (2007) 1278–1323] we derive closed-form expressions for Bayes estimators under the entropy and squared-error losses. The WPG family includes the classical inverse of the hyper inverse Wishart but has many more shape parameters, thus allowing for…

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