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癌症一级与二级预防效果的分别估计：皮肤自检与黑色素瘤病例对照研究AI 解读

Case-control studies increasingly have been used to evaluate the impact of cancer screening strategies. In this context the intent of the screening test has been to reduce cancer mortality by early detection of cancers, permitting curative therapy in some patients who would die of the disease if diagnosis were delayed until the disease was detected clinically. This phenomenon is known as secondary prevention. In an analysis of a case-control study of skin self-examination…

关于 Wei 临床试验偏置硬币设计的统计推断AI 解读

Wei (1988) analyzed data from a clinical trial in which an urn-sampling model was used to allocate patients to treatments. The trial resulted in 11 patients being allocated to the experimental treatment, all successes, and with one patient allocated to the control treatment, a failure. Wei analyzed these data using a randomization algorithm and concluded that the results were almost significant at p = 0·051. He asserted that an analysis which ignored the design and presumed…

关于 Wei 临床试验偏置硬币设计的统计推断AI 解读

Wei (1988) analyzed data from a clinical trial in which an urn-sampling model was used to allocate patients to treatments. The trial resulted in 11 patients being allocated to the experimental treatment, all successes, and with one patient allocated to the control treatment, a failure. Wei analyzed these data using a randomization algorithm and concluded that the results were almost significant at p = 0·051. He asserted that an analysis which ignored the design and presumed…