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A Risk Set Calibration Method for Failure Time Regression by Using a Covariate Reliability Sample

利用协变量可靠性样本的失效时间回归风险集校准法

Summary Regression parameter estimation in the Cox failure time model is considered when regression variables are subject to measurement error. Assuming that repeat regression vector measurements adhere to a classical measurement model, we can consider an ordinary regression calibration approach in which the unobserved covariates are replaced by an estimate of their conditional expectation given available covariate measurements. However, since the rate of withdrawal from the…

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Cox Regression with Accurate Covariates Unascertainable: A Nonparametric-Correction Approach

准确协变量无法获得时的 Cox 回归:非参数校正方法

Many survival studies involve covariates that are not accurately ascertainable; CD4 lymphocyte count in HIV/AIDS research is a typical example for which the gold standard of the measurement is not available. This article proposes a consistent estimation procedure for Cox regression under the additive measurement error model. Distinct from existing methods, the proposed estimation for regression coefficients does not require any additional assumptions. We establish the…

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Local linear regression for generalized linear models with missing data

缺失数据下广义线性模型的局部线性回归

Fan, Heckman and Wand proposed locally weighted kernel polynomial regression methods for generalized linear models and quasilikelihood functions. When the covariate variables are missing at random, we propose a weighted estimator based on the inverse selection probability weights. Distribution theory is derived when the selection probabilities are estimated nonparametrically. We show that the asymptotic variance of the resulting nonparametric estimator of the mean function…

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Weighted Semiparametric Estimation in Regression Analysis with Missing Covariate Data

协变量缺失回归中的加权半参数估计

This article investigates estimation of the regression coefficients in an assumed mean function when covariates on some subjects are missing. We examine the performance of a Horvitz and Thompson (1952)-type weighted estimator by using different estimates of the selection probabilities, which may be treated as nuisance parameters (or a nuisance function). In particular, we investigate the properties of the estimate of the regression parameters when the selection probabilities…

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Prospective Analysis of Logistic Case-Control Studies

Logistic 病例对照研究的前瞻式分析

In a classical case-control study, Prentice and Pyke proposed to ignore the study design and instead base estimation and inference on a random sampling (i.e., prospective) formulation. We generalize this prospective formulation of case-control studies to include multiplicative models, stratification, missing data, measurement error, robustness, and other examples. The resulting estimators, which ignore the case-control study aspect and instead are based on a random-sampling…

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Dimension Reduction in a Semiparametric Regression Model with Errors in Covariates

协变量含测量误差的半参数回归模型中的降维

We consider a semiparametric estimation method for general regression models when some of the predictors are measured with error. The technique relies on a kernel regression of the "true" covariate on all the observed covariates and surrogates. This requires a nonparametric regression in as many dimensions as there are covariates and surrogates. The usual theory copes with such higher-dimensional problems by using higher-order kernels, but this is unrealistic for most…

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On Robust Estimation in Logistic Case-Control Studies

病例对照研究中 Logistic 回归的稳健估计

Consider a logistic regression model under case-control sampling. Prentice & Pyke (1979) showed that the logistic slope estimates with case-control sampling may be estimated from a standard prospective logistic regression program and that the resulting standard errors are asymptotically correct. Since logistic regression estimates are nonrobust, we propose and analyze robust estimates of the slope parameters. We focus specifically on estimates which downweight observations…

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On robust estimation in logistic case-control studies

病例对照研究中逻辑回归的稳健估计

Consider a logistic regression model under case-control sampling. Prentice & Pyke (1979) showed that the logistic slope estimates with case-control sampling may be estimated from a standard prospective logistic regression program and that the resulting standard errors are asymptotically correct. Since logistic regression estimates are nonrobust, we propose and analyze robust estimates of the slope parameters. We focus specifically on estimates which downweight observations…

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