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Bayesian sparse multiple regression for simultaneous rank reduction and variable selection

同时实现降秩与变量选择的贝叶斯稀疏多响应回归

Summary We develop a Bayesian methodology aimed at simultaneously estimating low-rank and row-sparse matrices in a high-dimensional multiple-response linear regression model. We consider a carefully devised shrinkage prior on the matrix of regression coefficients which obviates the need to specify a prior on the rank, and shrinks the regression matrix towards low-rank and row-sparse structures. We provide theoretical support to the proposed methodology by proving minimax…

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Prediction of Protein Interdomain Linker Regions by a Nonstationary Hidden Markov Model

利用非平稳隐马尔可夫模型预测蛋白质结构域间连接区

Proteins have two types of regions: linker regions that connect active domains and nonlinker regions, which include domains and terminal residues. It is important to try to distinguish these regions using information in the sequence of amino acids that, when folded, form the protein. In this article we develop a nonstationary hidden Markov model to infer region boundaries. The approach is based on a latent variable defined on the sequence; this variable is a continuous index…

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Bayesian Curve Classification Using Wavelets

基于小波的贝叶斯曲线分类

We propose classification models for binary and multicategory data where the predictor is a random function. We use Bayesian modeling with wavelet basis functions that have nice approximation properties over a large class of functional spaces and can accommodate a wide variety of functional forms observed in real life applications. We develop an unified hierarchical model to encompass both the adaptive wavelet-based function estimation model and the logistic classification…

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Semiparametric Bayesian Analysis of Matched Case-Control Studies With Missing Exposure

暴露缺失时匹配病例对照研究的半参数贝叶斯分析

This article considers Bayesian analysis of matched case-control problems when one of the covariates is partially missing. Within the likelihood context, the standard approach to this problem is to posit a fully parametric model among the controls for the partially missing covariate as a function of the covariates in the model and the variables making up the strata. Sometimes the strata effects are ignored at this stage. Our approach differs not only in that it is Bayesian,…

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Analyzing Nonstationary Spatial Data Using Piecewise Gaussian Processes

利用分片高斯过程分析非平稳空间数据

In many problems in geostatistics the response variable of interest is strongly related to the underlying geology of the spatial location. In these situations there is often little correlation in the responses found in different rock strata, so the underlying covariance structure shows sharp changes at the boundaries of the rock types. Conventional stationary and nonstationary spatial methods are inappropriate, because they typically assume that the covariance between points…

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