Modelling Spatial Intensity for Replicated Inhomogeneous Point Patterns in Brain Imaging
脑成像中重复非均匀点模式的空间强度建模
Summary Pharmacological experiments in brain microscopy study patterns of cellular activ- ation in response to psychotropic drugs for connected neuroanatomic regions. A typical ex- perimental design produces replicated point patterns having highly complex spatial variability. Modelling this variability hierarchically can enhance the inference for comparing treatments. We propose a semiparametric formulation that combines the robustness of a nonparametric kernel method with…