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On an extension of the promotion time cure model

促进时间治愈模型的一种扩展

We consider the problem of estimating the distribution of time-to-event data that is subject to censoring and for which the event of interest might never occur, that is, some subjects are cured. To model this kind of data in the presence of covariates, one of the leading semiparametric models is the promotion time cure model (Stochastic Models of Tumor Latency and Their Biostatistical Applications (1996) World Scientific), which adapts the Cox model to the presence of cured…

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An Adapted Loss Function for Censored Quantile Regression

删失分位数回归的适配损失函数

In this article, we study a novel approach for the estimation of quantiles when facing potential right censoring of the responses. Contrary to the existing literature on the subject, the adopted strategy of this article is to tackle censoring at the very level of the loss function usually employed for the computation of quantiles, the so-called “check” function. For interpretation purposes, a simple comparison with the latter reveals how censoring is accounted for in the…

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Semiparametric Conditional Quantile Estimation Through Copula-Based Multivariate Models

基于 Copula 多元模型的半参数条件分位数估计

We consider a new approach in quantile regression modeling based on the copula function that defines the dependence structure between the variables of interest. The key idea of this approach is to rewrite the characterization of a regression quantile in terms of a copula and marginal distributions. After the copula and the marginal distributions are estimated, the new estimator is obtained as the weighted quantile of the response variable in the model. The proposed…

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Nonparametric estimation and inference for conditional density based Granger causality measures

基于条件密度的Granger因果度量:非参数估计与推断

We propose a nonparametric estimation and inference for conditional density based Granger causality measures that quantify linear and nonlinear Granger causalities. We first show how to write the causality measures in terms of copula densities. Thereafter, we suggest consistent estimators for these measures based on a consistent nonparametric estimator of copula densities. Furthermore, we establish the asymptotic normality of these nonparametric estimators and discuss the…

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Copula-Based Regression Estimation and Inference

基于 Copula 的回归估计与推断

We investigate a new approach to estimating a regression function based on copulas. The main idea behind this approach is to write the regression function in terms of a copula and marginal distributions. Once the copula and the marginal distributions are estimated, we use the plug-in method to construct our new estimator. Because various methods are available in the literature for estimating both a copula and a distribution, this idea provides a rich and flexible family of…

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EMPIRICAL LIKELIHOOD CONFIDENCE INTERVALS FOR DEPENDENT DURATION DATA

相依持续期数据的经验似然置信区间

Three types of confidence intervals are developed for a general class of functionals of a survival distribution based on censored dependent data. The confidence intervals are constructed via asymptotic normality (Wald’s method), the empirical likelihood (EL) method, and the blockwise EL method in which sample means over blocks of observations are used in place of the original data. Asymptotic results are derived to accurately calibrate the various procedures, and their…

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Local Polynomial Quantile Regression With Parametric Features

具有参数模型特征的局部多项式分位数回归

We propose a new approach to conditional quantile function estimation that combines both parametric and nonparametric techniques. At each design point, a global, possibly incorrect, pilot parametric model is locally adjusted through a kernel smoothing fit. The resulting quantile regression estimator behaves like a parametric estimator when the latter is correct and converges to the nonparametric solution as the parametric start deviates from the true underlying model. We…

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